The Dow Jones industrial average futures are down 71 points to 12,995 and Standard & Poor's 500 futures are off 9 points to 1,388.5. Nasdaq 100 futures are down 14 points to 2,721.25.
A Chinese manufacturing index inched lower in March, signaling for the second time in as many months that its manufacturing sector is contracting.
Asian markets were already in decline when a survey in Europe of the services and manufacturing sectors suggested things may be worse than thought.
Those numbers are outweighing a strong earnings gain at FedEx Corp. and ahead of what is expected to be a positive U.S. jobs report.
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